作者：张惠静, 毕颖楠, 郝敦玲
作者单位：第三军医大学医学检验系分析化学教研室, 重庆 400038
关键词：循环肿瘤细胞; 检测; 微流控芯片
摘要：
循环肿瘤细胞(circulating tumor cells,ctcs)存在于肿瘤患者外周血中,特异、敏感地检测ctcs对肿瘤患者的预后评价和临床的个体化治疗均有重要意义。该文在综述ctcs的富集、筛选和鉴定技术的基础之上,对微流控芯片技术在这一领域的应用做了重点阐述。
the development and prospect of circulating tumour cells detection
zhang hui-jing, bi ying-nan, hao dun-ling
department of analytical chemistry, faculty of laboratory medicine, the third military medical university, chongqing 400038, china
abstract: circulating tumor cells (ctcs) exist in peripheral blood of tumor patients. to detect ctcs specifically and sensitively is important to prognosis evaluation and individual therapy for the tumor patients. this review overviews the enriching, screening and identifying technology of ctcs, and particularly represents the application of microfluidic chip technology in this domain.
keywords: circulating tumor cells; detection; microfluidic chip
2015, 36(5): 1-4 收稿日期: 2010-4-28;收到修改稿日期: 2010-7-6
基金项目: 重庆市科技攻关重点资助项目(cstc2009ab5198)
作者简介: 张惠静(1963-),女,重庆市人,教授,博士,主要研究方向为分子识别的物质基础及新型诊断技术。
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